Anita M van den Hoek Selected Research

icosabutate

11/2020	Dual targeting of hepatic fibrosis and atherogenesis by icosabutate, an engineered eicosapentaenoic acid derivative.
2/2020	Icosabutate Exerts Beneficial Effects Upon Insulin Sensitivity, Hepatic Inflammation, Lipotoxicity, and Fibrosis in Mice.

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Anita M van den Hoek Research Topics

Disease

11	Inflammation (Inflammations) 11/2021 - 01/2012
11	Insulin Resistance 01/2021 - 01/2004
7	Fibrosis (Cirrhosis) 11/2021 - 11/2015
6	Atherosclerosis 11/2021 - 01/2010
6	Dyslipidemias (Dyslipidemia) 01/2019 - 01/2011
5	Obesity 01/2021 - 01/2011
5	Body Weight (Weight, Body) 01/2019 - 01/2004
4	Type 2 Diabetes Mellitus (MODY) 01/2019 - 03/2014
3	Fatty Liver 11/2021 - 05/2014
3	Alcoholic Fatty Liver 11/2021 - 11/2015
3	Hyperlipidemias (Hyperlipidemia) 01/2021 - 01/2019
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2019 - 01/2012
3	Weight Gain 11/2015 - 05/2013
2	Non-alcoholic Fatty Liver Disease 02/2020 - 01/2013
2	Hypertrophy 02/2020 - 05/2014
2	Hyperinsulinism (Hyperinsulinemia) 01/2020 - 10/2004
2	Weight Loss (Weight Reduction) 12/2014 - 01/2012
2	Hypercholesterolemia 01/2012 - 01/2011
2	Hypertension (High Blood Pressure) 01/2012 - 01/2011
1	Liver Diseases (Liver Disease) 11/2021
1	Frailty 01/2020
1	Muscular Atrophy (Muscle Atrophy) 01/2019
1	Diabetes Complications 01/2019
1	Liver Cirrhosis (Hepatic Cirrhosis) 12/2018
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2017
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2017
1	Glucose Intolerance 05/2015
1	Hyperglycemia 05/2013
1	Overweight 01/2011
1	Skin Abnormalities 01/2004

Drug/Important Bio-Agent (IBA)

9	LipidsIBA 11/2021 - 01/2011
9	Apolipoproteins E (ApoE)IBA 01/2021 - 01/2010
9	CholesterolIBA 11/2020 - 01/2004
9	Glucose (Dextrose)FDA LinkGeneric 02/2020 - 01/2004
5	Insulin (Novolin)FDA Link 05/2013 - 01/2004
3	Pharmaceutical PreparationsIBA 01/2019 - 01/2011
3	Triglycerides (Triacylglycerol)IBA 05/2015 - 01/2004
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2021 - 02/2020
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2018
2	icosabutateIBA 11/2020 - 02/2020
2	Eicosapentaenoic AcidIBA 11/2020 - 02/2020
2	obeticholic acidIBA 11/2020 - 12/2018
2	Rosiglitazone (Avandia)FDA Link 02/2020 - 01/2004
2	salicylsalicylic acid (salsalate)IBA 11/2015 - 05/2015
2	Atorvastatin (Lipitor)FDA Link 10/2014 - 01/2012
2	Nonesterified Fatty Acids (NEFA)IBA 05/2013 - 01/2004
2	RimonabantIBA 01/2012 - 01/2011
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2007 - 01/2004
1	2- (2,6- dimethyl- 4- (3- (4- (methylthio)phenyl)- 3- oxo- 1- propenyl)phenoxyl)- 2- methylpropanoic acidIBA 01/2021
1	Phospholipids (Phosphatides)FDA LinkGeneric 11/2020
1	Islet Amyloid PolypeptideIBA 11/2020
1	FructoseIBA 11/2020
1	Arachidonic Acid (Vitamin F)IBA 11/2020
1	Pioglitazone (Actos)FDA Link 02/2020
1	Fenofibrate (CiL)FDA LinkGeneric 02/2020
1	Alanine Transaminase (SGPT)IBA 01/2020
1	acylcarnitineIBA 01/2020
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2020
1	GlucokinaseIBA 01/2019
1	CollagenIBA 12/2018
1	propagermanium (Ge 132)IBA 01/2017
1	CannabinoidsIBA 12/2014
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 10/2014
1	alirocumabIBA 10/2014
1	CarbohydratesIBA 05/2014
1	Peroxidase (Myeloperoxidase)IBA 05/2014
1	Transcription Factors (Transcription Factor)IBA 05/2014
1	LipopolysaccharidesIBA 05/2014
1	InterleukinsIBA 05/2014
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 05/2014
1	Metformin (Glucophage)FDA LinkGeneric 03/2014
1	Blood Glucose (Blood Sugar)IBA 05/2013
1	cholebine (colestilan)IBA 05/2013
1	Bile Acids and Salts (Bile Acids)IBA 05/2013
1	SUB885CIBA 01/2012
1	C 39 (C39)IBA 01/2012
1	aliskiren FDA Link 01/2012
1	Renin InhibitorsIBA 01/2012
1	Cholesterol Ester Transfer ProteinsIBA 01/2011
1	CNTO 530IBA 01/2011
1	Apolipoprotein E3IBA 01/2011
1	low density lipoprotein inhibitorIBA 01/2010
1	Neuropeptide YIBA 09/2008
1	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 08/2004
1	Apolipoprotein C-I (Apolipoprotein C1)IBA 01/2004

Therapy/Procedure

2	Therapeutics 11/2021 - 01/2018
1	Drug Therapy (Chemotherapy) 11/2021
1	Caloric Restriction 01/2019